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Therapeutic inhibition of RAS in non-small cell lung cancer

Oncogenic KRAS mutations are the most common driver event in NSCLC, occurring in up to 30% of patients. Direct strategies to target KRAS (and other RAS isoforms) met with consistent failure until the discovery of covalent KRAS G12C inhibitors, leading to a first-in-class FDA accelerated approval for...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Katherine B. Nichols, Benjamin O. Herzberg
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2026-06-01
Rangatū:Frontiers in Oncology
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fonc.2026.1817943/full
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