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Identification and validation of plasma protein biomarkers as therapeutic targets in acute myeloid leukemia: an integrative multi-omics study

IntroductionAcute myeloid leukemia (AML) remains a therapeutic challenge due to its high relapse rate and limited treatment options. This study aimed to identify and validate novel circulating protein biomarkers with causal roles in AML pathogenesis using an integrative multi-omics approach.MethodsW...

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Автори: Linhui Hu, Qingqing Luo, Ya Liao, Zhimin Zhai, Yangyang Ding, Yan Fei
Формат: Artigo
Мова:Inglês
Опубліковано: Frontiers Media S.A. 2025-10-01
Серія:Frontiers in Immunology
Предмети:
acute myeloid leukemia
Mendelian randomization
plasma proteins
therapeutic targets
multi-omics
Онлайн доступ:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1659811/full
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