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In vivo quantification of neurofibrillary tangles with [18F]MK-6240

Abstract Background Imaging agents capable of quantifying the brain’s tau aggregates will allow a more precise staging of Alzheimer’s disease (AD). The aim of the present study was to examine the in vitro properties as well as the in vivo kinetics, using gold standard methods, of the novel positron...

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Autori principali: Tharick A. Pascoal, Monica Shin, Min Su Kang, Mira Chamoun, Daniel Chartrand, Sulantha Mathotaarachchi, Idriss Bennacef, Joseph Therriault, Kok Pin Ng, Robert Hopewell, Reda Bouhachi, Hung-Hsin Hsiao, Andrea L. Benedet, Jean-Paul Soucy, Gassan Massarweh, Serge Gauthier, Pedro Rosa-Neto
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2018-07-01
Serie:Alzheimer’s Research & Therapy
Soggetti:
Tau positron emission tomography
Neurofibrillary tangles
Alzheimer’s disease
Accesso online:http://link.springer.com/article/10.1186/s13195-018-0402-y
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