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Saporin-S6: A Useful Tool in Cancer Therapy

Thirty years ago, the type 1 ribosome-inactivating protein (RIP) saporin-S6 (also known as saporin) was isolated from Saponaria officinalis L. seeds. Since then, the properties and mechanisms of action of saporin-S6 have been well characterized, and it has been widely employed in the construction of...

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Główni autorzy: Letizia Polito, Massimo Bortolotti, Daniele Mercatelli, Maria Giulia Battelli, Andrea Bolognesi
Format: Artigo
Język:Inglês
Wydane: MDPI AG 2013-10-01
Seria:Toxins
Hasła przedmiotowe:
saporin-S6
saporin
Saponaria officinalis
immunotoxin
immunotherapy
ribosome-inactivating proteins
monoclonal antibodies
rRNA N-glycosylase activity
anti-cancer therapy
hematological tumors
Dostęp online:http://www.mdpi.com/2072-6651/5/10/1698
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