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Two Saporin-Containing Immunotoxins Specific for CD20 and CD22 Show Different Behavior in Killing Lymphoma Cells

Immunotoxins (ITs) are hybrid proteins combining the binding specificity of antibodies with the cytocidal properties of toxins. They represent a promising approach to lymphoma therapy. The cytotoxicity of two immunotoxins obtained by chemical conjugation of the plant toxin saporin-S6 with the anti-C...

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Autori principali: Letizia Polito, Daniele Mercatelli, Massimo Bortolotti, Stefania Maiello, Alice Djemil, Maria Giulia Battelli, Andrea Bolognesi
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2017-05-01
Serie:Toxins
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Accesso online:http://www.mdpi.com/2072-6651/9/6/182
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