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A bispecific antibody AP203 targeting PD-L1 and CD137 exerts potent antitumor activity without toxicity

Abstract Background Bispecific antibody has garnered considerable attention in the recent years due to its impressive preliminary efficacy in hematological malignancies. For solid tumors, however, the main hindrance is the suppressive tumor microenvironment, which effectively impedes the activation...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Po-Lin Huang, Hung-Tsai Kan, Ching-Hsuan Hsu, Hsin-Ta Hsieh, Wan-Chien Cheng, Ren-Yeong Huang, Jhong-Jhe You
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMC 2023-05-01
Cyfres:Journal of Translational Medicine
Pynciau:
Mynediad Ar-lein:https://doi.org/10.1186/s12967-023-04193-5
Tagiau: Ychwanegu Tag
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