A Novel Anti-B7-H3 × Anti-CD3 Bispecific Antibody with Potent Antitumor Activity

B7-H3 plays an important role in tumor apoptosis, proliferation, adhesion, angiogenesis, invasion, migration, and evasion of immune surveillance. It is overexpressed in various human solid tumor tissues. In patients, B7-H3 overexpression correlates with advanced stages, poor clinical outcomes, and r...

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Hlavní autoři:	Yan Feng, Kun Xie, Yanxin Yin, Bingyu Li, Chenyu Pi, Xiaoqing Xu, Tao Huang, Jingming Zhang, Bo Wang, Hua Gu, Jianmin Fang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2022-01-01
Edice:	Life
Témata:	B7-H3 bispecific T cell engager solid tumor immunotherapy
On-line přístup:	https://www.mdpi.com/2075-1729/12/2/157
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