mRNA-LNP expressing PfCSP and Pfs25 vaccine candidates targeting infection and transmission of Plasmodium falciparum

Abstract Malaria is a deadly disease responsible for between 550,000 and 627,000 deaths annually. There is a pressing need to develop vaccines focused on malaria elimination. The complex lifecycle of Plasmodium falciparum provides opportunities not only to target the infectious sporozoite stage, int...

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Autores principales:	Clifford T. H. Hayashi, Yi Cao, Leor C. Clark, Abhai K. Tripathi, Fidel Zavala, Garima Dwivedi, James Knox, Mohamad-Gabriel Alameh, Paulo J. C. Lin, Ying K. Tam, Drew Weissman, Nirbhay Kumar
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2022-12-01
Colección:	npj Vaccines
Acceso en línea:	https://doi.org/10.1038/s41541-022-00577-8
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