Messenger RNA expressing PfCSP induces functional, protective immune responses against malaria in mice

Abstract Human malaria affects the vast majority of the world’s population with the Plasmodium falciparum species causing the highest rates of morbidity and mortality. With no licensed vaccine and leading candidates achieving suboptimal protection in the field, the need for an effective immunoprophy...

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Autors principals:	Katherine L. Mallory, Justin A. Taylor, Xiaoyan Zou, Ishita N. Waghela, Cosette G. Schneider, Michael Q. Sibilo, Neeraja M. Punde, Leah C. Perazzo, Tatyana Savransky, Martha Sedegah, Sheetij Dutta, Chris J. Janse, Norbert Pardi, Paulo J. C. Lin, Ying K. Tam, Drew Weissman, Evelina Angov
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2021-06-01
Col·lecció:	npj Vaccines
Accés en línia:	https://doi.org/10.1038/s41541-021-00345-0
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