Pharmacological modulation of CXCL12/CXCR4/ACKR3 for brain disorders – an overview
Abstract The CXCL12/CXCR4/ACKR3 axis is essential for brain development and homeostasis. Dysregulation of CXCL12 or its receptors has been associated with various CNS disorders related to neurodevelopmental defects, neuroinflammation, neurodegeneration and brain tumors. This signaling axis represent...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMC
2026-04-01
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| Col·lecció: | Cell Communication and Signaling |
| Matèries: | |
| Accés en línia: | https://doi.org/10.1186/s12964-026-02877-1 |
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