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Connexin hemichannels with prostaglandin release in anabolic function of bone to mechanical loading

Mechanical stimulation, such as physical exercise, is essential for bone formation and health. Here, we demonstrate the critical role of osteocytic Cx43 hemichannels in anabolic function of bone in response to mechanical loading. Two transgenic mouse models, R76W and Δ130–136, expressing dominant-ne...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Dezhi Zhao, Manuel A Riquelme, Teja Guda, Chao Tu, Huiyun Xu, Sumin Gu, Jean X Jiang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications Ltd 2022-02-01
Sarja:eLife
Aiheet:
Linkit:https://elifesciences.org/articles/74365
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