Tissue factor targeting peptide enhances nanoparticle binding and delivery of a synthetic specialized pro-resolving lipid mediator to injured arteries

Background: Specialized pro-resolving lipid mediators (SPM) such as resolvin D1 (RvD1) attenuate inflammation and exhibit vasculo-protective properties. Methods: We investigated poly-lactic-co-glycolic acid (PLGA)-based nanoparticles (NP), containing a peptide targeted to tissue factor (TF) for deli...

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Autors principals:	Elizabeth S. Levy, PhD, Alexander S. Kim, MD, Evan Werlin, MD, Mian Chen, MD, Brian E. Sansbury, PhD, Matthew Spite, PhD, Tejal A. Desai, PhD, Michael S. Conte, MD
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2023-01-01
Col·lecció:	JVS - Vascular Science
Matèries:	Resolution Inflammation Specialized pro-resolving lipid mediators (SPM) Resolvin D1 (RvD1) Peripheral arterial disease (PAD) Nanoparticle
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2666350323000305
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