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Neuroprotective Potential of Synthetic Mono-Carbonyl Curcumin Analogs Assessed by Molecular Docking Studies

Cognitive decline in dementia is associated with deficiency of the cholinergic system. In this study, five mono-carbonyl curcumin analogs were synthesized, and on the basis of their promising in vitro anticholinesterase activities, they were further investigated for in vivo neuroprotective and memor...

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Principais autores: Haya Hussain, Shujaat Ahmad, Syed Wadood Ali Shah, Mehreen Ghias, Abid Ullah, Shafiq Ur Rahman, Zul Kamal, Farman Ali Khan, Nasir Mehmood Khan, Juma Muhammad, Mazen Almehmadi, Osama Abdulaziz, Saad Alghamdi
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-11-01
Serier:Molecules
Fag:
mono-carbonyl curcumin analogs
cholinesterases
molecular docking
amnesia
scopolamine
EPM
Online adgang:https://www.mdpi.com/1420-3049/26/23/7168
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