Variant-to-Gene-Mapping Analyses Reveal a Role for the Hypothalamus in Genetic Susceptibility to Inflammatory Bowel DiseaseSummary

Background & Aims: Inflammatory bowel disease (IBD) is a polygenic disorder characterized principally by dysregulated inflammation impacting the gastrointestinal tract. However, there also is increasing evidence for a clinical association with stress and depression. Given the role of the hypotha...

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Κύριοι συγγραφείς:	Chiara Lasconi, Matthew C. Pahl, Diana L. Cousminer, Claudia A. Doege, Alessandra Chesi, Kenyaita M. Hodge, Michelle E. Leonard, Sumei Lu, Matthew E. Johnson, Chun Su, Reza K. Hammond, James A. Pippin, Natalie A. Terry, Louis R. Ghanem, Rudolph L. Leibel, Andrew D. Wells, Struan F.A. Grant
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Elsevier 2021-01-01
Σειρά:	Cellular and Molecular Gastroenterology and Hepatology
Θέματα:	HPA Stress Colonoids hESC
Διαθέσιμο Online:	http://www.sciencedirect.com/science/article/pii/S2352345X20301673
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