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The nucleolar shell provides anchoring sites for DNA untwisting

Abstract DNA underwinding (untwisting) is a crucial step in transcriptional activation. DNA underwinding occurs between the site where torque is generated by RNA polymerase (RNAP) and the site where the axial rotation of DNA is constrained. However, what constrains DNA axial rotation in the nucleus...

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Bibliografiske detaljer
Principais autores: Jumpei Fukute, Koichiro Maki, Taiji Adachi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2024-01-01
Serier:Communications Biology
Online adgang:https://doi.org/10.1038/s42003-023-05750-w
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