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Sarcopenia associates with SNAP-25 SNPs and a miRNAs profile which is modulated by structured rehabilitation treatment

Abstract Background Sarcopenia is a loss of muscle mass and strength causing disability, morbidity, and mortality in older adults, which is characterized by alterations of the neuromuscular junctions (NMJs). SNAP-25 is essential for the maintenance of NMJ integrity, and the expression of this protei...

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Main Authors: Simone Agostini, Roberta Mancuso, Andrea Saul Costa, Franca Rosa Guerini, Fabio Trecate, Rossella Miglioli, Elisabetta Menna, Beatrice Arosio, Mario Clerici, the SA. M. B. A. project
Format: Artigo
Language:Inglês
Published: BMC 2021-07-01
Series:Journal of Translational Medicine
Subjects:
Sarcopenia
Rehabilitation
SNAP-25
miRNAs
Biomarkers
Online Access:https://doi.org/10.1186/s12967-021-02989-x
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