Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

N6‐methyladenosine (m6A) modifications accelerate microRNA (miRNA) biogenesis by promoting the processing of m6A‐modified primary miRNAs (pri‐miRNAs). However, the regulatory mechanism of m6A modification of pri‐miRNA remains unclear. Here, we found that NF90‐NF45 acts as a negative regulator of the...

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Manylion Llyfryddiaeth

Prif Awduron:	Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Wiley 2026-05-01
Cyfres:	FEBS Open Bio
Pynciau:	miRNA biogenesis RNA binding protein RNA metabolism RNA methylation RNA methyltransferase RNA modification
Mynediad Ar-lein:	https://doi.org/10.1002/2211-5463.70173
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!