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HIC1 links retinoic acid signalling to group 3 innate lymphoid cell-dependent regulation of intestinal immunity and homeostasis.

The intestinal immune system must be able to respond to a wide variety of infectious organisms while maintaining tolerance to non-pathogenic microbes and food antigens. The Vitamin A metabolite all-trans-retinoic acid (atRA) has been implicated in the regulation of this balance, partially by regulat...

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Hlavní autoři: Kyle Burrows, Frann Antignano, Alistair Chenery, Michael Bramhall, Vladimir Korinek, T Michael Underhill, Colby Zaph
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2018-02-01
Edice:PLoS Pathogens
On-line přístup:https://doi.org/10.1371/journal.ppat.1006869
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