Disruption of zebrafish sex differentiation by emerging contaminants hexafluoropropylene oxides at environmental concentrations via antagonizing androgen receptor pathways

As alternatives of perfluorooctanoic acid (PFOA), hexafluoropropylene oxide dimeric acid (HFPO-DA) and trimeric acid (HFPO-TA) have been detected increasingly in environmental media and even humans. They have been shown to exhibit reproductive toxicity to model species, but their effects on human re...

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Principais autores:	Tingyu Lu, Wei Zheng, Fanglin Hu, Xicha Lin, Ran Tao, Minjie Li, Liang-Hong Guo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-08-01
coleção:	Environment International
Assuntos:	Hexafluoropropylene oxide Perfluorooctanoic acid Sex differentiation Zebrafish Androgen receptor Antagonist
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0160412024004549
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