Hexafluoropropylene oxide trimer acid (HFPO-TA) exposure predisposes to MASLD through reprogramming hepatic epigenome and transcriptome

Substitute for perfluorooctanoic acid (PFOA), like hexafluoropropylene oxide trimer acid (HFPO-TA), are sparking growing environmental and health worries because of their persistence and capacity for bioaccumulation. Here, we employed an integrated multi-omics approach to systematically investigate...

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Autors principals:	Jiao Yu, Mengan Guo, Qiaoli Zhou, Lina Xue, Wenhua Wang, Xiao Wu, Yufeng Qin, Wei Gu, Guizhen Du
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2026-03-01
Col·lecció:	Ecotoxicology and Environmental Safety
Matèries:	HFPO-TA PFAS Multi-omics MASLD Epigenome Nuclear Receptors
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S0147651326002691
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