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ELK1 uses different DNA binding modes to regulate functionally distinct classes of target genes.

Eukaryotic transcription factors are grouped into families and, due to their similar DNA binding domains, often have the potential to bind to the same genomic regions. This can lead to redundancy at the level of DNA binding, and mechanisms are required to generate specific functional outcomes that e...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Zaneta Odrowaz, Andrew D Sharrocks
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2012-01-01
Schriftenreihe:PLoS Genetics
Online-Zugang:http://europepmc.org/articles/PMC3349735?pdf=render
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