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ELK1 uses different DNA binding modes to regulate functionally distinct classes of target genes.

Eukaryotic transcription factors are grouped into families and, due to their similar DNA binding domains, often have the potential to bind to the same genomic regions. This can lead to redundancy at the level of DNA binding, and mechanisms are required to generate specific functional outcomes that e...

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Autori principali: Zaneta Odrowaz, Andrew D Sharrocks
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2012-01-01
Serie:PLoS Genetics
Accesso online:http://europepmc.org/articles/PMC3349735?pdf=render
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