Hippocampal PACAP signaling activation triggers a rapid antidepressant response

Abstract Background The development of ketamine-like rapid antidepressants holds promise for enhancing the therapeutic efficacy of depression, but the underlying cellular and molecular mechanisms remain unclear. Implicated in depression regulation, the neuropeptide pituitary adenylate cyclase-activa...

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Bibliografiske detaljer

Principais autores:	Hai-Lou Zhang, Yan Sun, Zhang-Jie Wu, Ying Yin, Rui-Yi Liu, Ji-Chun Zhang, Zhang-Jin Zhang, Suk-Yu Yau, Hao-Xin Wu, Ti-Fei Yuan, Li Zhang, Miroslav Adzic, Gang Chen
Format:	Artigo
Sprog:	Inglês
Udgivet:	KeAi Communications Co., Ltd. 2024-07-01
Serier:	Military Medical Research
Fag:	Antidepressant response Pituitary adenylate cyclase-activating polypeptide (PACAP) Ketamine Optogenetic Novelty suppressed feeding (NSF)
Online adgang:	https://doi.org/10.1186/s40779-024-00548-1
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