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Hippocampal PACAP signaling activation triggers a rapid antidepressant response

Abstract Background The development of ketamine-like rapid antidepressants holds promise for enhancing the therapeutic efficacy of depression, but the underlying cellular and molecular mechanisms remain unclear. Implicated in depression regulation, the neuropeptide pituitary adenylate cyclase-activa...

Täydet tiedot

Tallennettuna:
Päätekijät: Hai-Lou Zhang, Yan Sun, Zhang-Jie Wu, Ying Yin, Rui-Yi Liu, Ji-Chun Zhang, Zhang-Jin Zhang, Suk-Yu Yau, Hao-Xin Wu, Ti-Fei Yuan, Li Zhang, Miroslav Adzic, Gang Chen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: KeAi Communications Co., Ltd. 2024-07-01
Sarja:Military Medical Research
Aiheet:
Antidepressant response
Pituitary adenylate cyclase-activating polypeptide (PACAP)
Ketamine
Optogenetic
Novelty suppressed feeding (NSF)
Linkit:https://doi.org/10.1186/s40779-024-00548-1
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