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Comparison of Antibodies with Amylase Activity from Cerebrospinal Fluid and Serum of Patients with Multiple Sclerosis.

We have recently shown that IgGs from serum and cerebrospinal fluid (CSF) of MS patients are active in hydrolysis of DNA and myelin basic protein. According to literature data, anti-DNA and anti-MBP abzymes may promote important neuropathologic mechanisms in this chronic inflammatory disorder and in...

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Bibliografiske detaljer
Principais autores: Vasilii B Doronin, Taisiya A Parkhomenko, Massimiliano Castellazzi, Edward Cesnik, Valentina N Buneva, Enrico Granieri, Georgy A Nevinsky
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2016-01-01
Serier:PLoS ONE
Online adgang:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0154688&type=printable
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