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Exploring the in vitro and in vivo anticancer activity of lasiokaurin on nasopharyngeal carcinoma

Objective: To evaluate the anticancer activity of the natural diterpenoid lasiokaurin (LAS) against nasopharyngeal carcinoma (NPC) both in vitro and in vivo, along with investigating its underlying mechanism. Methods: MTT and colony formation assays were used to assess cell viability. Flow cytometry...

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Principais autores: Huanhuan Pu, Jinrong Lin, Li-Sha Shen, Yu-Shan Lin, Rui-Hong Gong, Guo Qing Chen, Sibao Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2023-12-01
coleção:Pharmacological Research - Modern Chinese Medicine
Assuntos:
Lasiokaurin
Nasopharyngeal carcinoma
Apoptosis
Cell cycle arrest
Migration
Invasion
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2667142523000891
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