Binding Studies of AICAR and Human Serum Albumin by Spectroscopic, Theoretical, and Computational Methodologies

The interactions of small molecule drugs with plasma serum albumin are important because of the influence of such interactions on the pharmacokinetics of these therapeutic agents. 5-Aminoimidazole-4-carboxamide ribonucleoside (AICAR) is one such drug candidate that has recently gained attention for...

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Hlavní autoři:	Shokoufeh Hashempour, Nahid Shahabadi, Aishat Adewoye, Brennen Murphy, Camaray Rouse, Brian A. Salvatore, Christopher Stratton, Elahe Mahdavian
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2020-11-01
Edice:	Molecules
Témata:	AICAR human serum albumin (HSA) static fluorescence quenching synchronous fluorescence 3D fluorescence FRET
On-line přístup:	https://www.mdpi.com/1420-3049/25/22/5410
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