The transcription factor CREM drives an inflammatory phenotype of T cells in oligoarticular juvenile idiopathic arthritis

Abstract Background Inflammatory effector T cells trigger inflammation despite increased numbers of Treg cells in the synovial joint of patients suffering from juvenile idiopathic arthritis (JIA). The cAMP response element (CREM)α is known to play a major role in regulation of T cells in SLE, coliti...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Kim Ohl, Helge Nickel, Halima Moncrieffe, Patricia Klemm, Anja Scheufen, Dirk Föll, Viktor Wixler, Angela Schippers, Norbert Wagner, Lucy R. Wedderburn, Klaus Tenbrock
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2018-06-01
Цуврал:	Pediatric Rheumatology Online Journal
Нөхцлүүд:	CREM JIA Effector T cells
Онлайн хандалт:	http://link.springer.com/article/10.1186/s12969-018-0253-x
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!