Time-resolved RNA-seq analysis to unravel the in vivo competence induction by Streptococcus pneumoniae during pneumonia-derived sepsis

ABSTRACTCompetence development in Streptococcus pneumoniae (pneumococcus) is tightly intertwined with virulence. In addition to genes encoding genetic transformation machinery, the competence regulon also regulates the expression of allolytic factors, bacteriocins, and cytotoxins. Pneumococcal compe...

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Principais autores:	Myung Whan Oh, Jingjun Lin, Sook Yin Chong, Shi Qian Lew, Tauqeer Alam, Gee W. Lau
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology 2024-03-01
Series:	Microbiology Spectrum
Assuntos:	Streptococcus pneumoniae pneumonia-derived sepsis RNA-seq competent state host adaptation Pht histidine triad proteins
Acceso en liña:	https://journals.asm.org/doi/10.1128/spectrum.03050-23
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