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Influence of DNA Mismatch Repair (MMR) System in Survival and Response to Immune Checkpoint Inhibitors (ICIs) in Non-Small Cell Lung Cancer (NSCLC): Retrospective Analysis

Mutations in the mismatch repair (MMR) system predict the response to immune checkpoint inhibitors (ICIs) like colon or gastric cancer. However, the MMR system’s involvement in non-small cell lung cancer (NSCLC) remains unknown. Addressing this issue will improve clinical guidelines in the case of m...

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Autori principali: Alejandro Olivares-Hernández, Edel del Barco Morillo, Carmen Parra Pérez, José Pablo Miramontes-González, Luis Figuero-Pérez, Teresa Martín-Gómez, Roberto Escala-Cornejo, Lorena Bellido Hernández, Rogelio González Sarmiento, Juan Jesús Cruz-Hernández, María Dolores Ludeña de la Cruz
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2022-02-01
Serie:Biomedicines
Soggetti:
MMR system
immunotherapy
ICIs
NSCLC
dMMR/MSI-H
survival
Accesso online:https://www.mdpi.com/2227-9059/10/2/360
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