DNA mismatch repair defect and intratumor heterogeneous deficiency differently impact immune responses in diffuse large B-cell lymphoma

Deficient (d) DNA mismatch repair (MMR) is a biomarker predictive of better response to PD-1 blockade immunotherapy in solid tumors. dMMR can be caused by mutations in MMR genes or by protein inactivation, which can be detected by sequencing and immunohistochemistry, respectively. To investigate the...

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Үндсэн зохиолчид:	Zijun Y. Xu-Monette, Cancan Luo, Li Yu, Yong Li, Govind Bhagat, Alexandar Tzankov, Carlo Visco, Xiangshan Fan, Karen Dybkaer, Ali Sakhdari, Nicholas T. Wang, Alyssa F. Yuan, April Chiu, Wayne Tam, Youli Zu, Eric D. Hsi, Anamarija M. Perry, Wenting Song, Dennis O’Malley, Qingyan Au, Harry Nunns, Heounjeong Go, Michael B. Møller, Benjamin M. Parsons, Santiago Montes-Moreno, Maurilio Ponzoni, Andrés J.M. Ferreri, Aliyah R. Sohani, Jeremy S. Abramson, Bing Xu, Ken H. Young
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Taylor & Francis Group 2024-12-01
Цуврал:	OncoImmunology
Нөхцлүүд:	DNA mismatch repair dMMR PD-1 DLBCL immune MSH6
Онлайн хандалт:	https://www.tandfonline.com/doi/10.1080/2162402X.2024.2384667
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!