Matrix Metalloproteinase 2 and 9 Enzymatic Activities are Selectively Increased in the Myocardium of Chronic Chagas Disease Cardiomyopathy Patients: Role of TIMPs

Chronic Chagas disease (CCC) is an inflammatory dilated cardiomyopathy with a worse prognosis compared to other cardiomyopathies. We show the expression and activity of Matrix Metalloproteinases (MMP) and of their inhibitors TIMP (tissue inhibitor of metalloproteinases) in myocardial samples of end...

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Detalhes bibliográficos

Principais autores:	Monique Andrade Baron, Ludmila Rodrigues Pinto Ferreira, Priscila Camillo Teixeira, Ana Iochabel Soares Moretti, Ronaldo Honorato Barros Santos, Amanda Farage Frade, Andréia Kuramoto, Victor Debbas, Luiz Alberto Benvenuti, Fabio Antônio Gaiotto, Fernando Bacal, Pablo Pomerantzeff, Christophe Chevillard, Jorge Kalil, Edecio Cunha-Neto
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-03-01
coleção:	Frontiers in Cellular and Infection Microbiology
Assuntos:	Chagas disease metalloproteinases MMP heart failure cardiac remodeling cardiomyopathy
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fcimb.2022.836242/full
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