STING Signaling Drives Production of Innate Cytokines, Generation of CD8+ T Cells and Enhanced Protection Against Trypanosoma cruzi Infection

A variety of signaling pathways are involved in the induction of innate cytokines and CD8+ T cells, which are major players in protection against acute Trypanosoma cruzi infection. Previous data have demonstrated that a TBK-1/IRF3-dependent signaling pathway promotes IFN-β production in response to...

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Prif Awduron:	Raquel de Souza Vieira, Marilda Savoia Nascimento, Isaú Henrique Noronha, José Ronnie Carvalho Vasconcelos, Luiz Alberto Benvenuti, Glen N. Barber, Niels Olsen Saraiva Câmara, Jorge Kalil, Edecio Cunha-Neto, Rafael Ribeiro Almeida
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Frontiers Media S.A. 2022-01-01
Cyfres:	Frontiers in Immunology
Pynciau:	STING IFN-β IL-6 IL-12 CD8+ T cell Trypanosoma cruzi
Mynediad Ar-lein:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.775346/full
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!