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Activation and Inhibition of Human Matrix Metalloproteinase-9 (MMP9) by HOCl, Myeloperoxidase and Chloramines

Matrix metalloproteinase-9 (MMP9, gelatinase B) plays a key role in the degradation of extracellular-matrix (ECM) proteins in both normal physiology and multiple pathologies, including those linked with inflammation. MMP9 is excreted as an inactive proform (proMMP9) by multiple cells, and particular...

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Autores principales: Yihe Wang, Christine Y. Chuang, Clare L. Hawkins, Michael J. Davies
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2022-08-01
Colección:Antioxidants
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Acceso en línea:https://www.mdpi.com/2076-3921/11/8/1616
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