Selenocyanate (SeCN−) acts as an efficient competitive substrate for myeloperoxidase and decreases biological damage induced by hypochlorous acid

The leukocyte-derived enzyme myeloperoxidase (MPO) is a key component of the innate immune response and mediates the killing of pathogens via the generation of the powerful oxidant hypochlorous acid (HOCl). Unintended or excessive formation of this species can however result in damage to host tissue...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Xing Zhang, Shuqi Xu, Christine Y. Chuang, Brian J. Day, Clare L. Hawkins, Michael J. Davies
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Elsevier 2024-04-01
Sarja:	Redox Biochemistry and Chemistry
Aiheet:	Myeloperoxidase Hypochlorous acid Extracellular matrix Selenocyanate Thiocyanate Fibronectin
Linkit:	http://www.sciencedirect.com/science/article/pii/S2773176623000172
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