Preclinical evaluation of a bivalent conjugate vaccine against Salmonella Typhi and Paratyphi A

IntroductionSalmonella enterica serovars Typhi and Paratyphi A cause millions of cases and thousands of deaths annually, predominantly affecting children in South and Southeast Asia. Following the licensure and World Health Organization (WHO) prequalification of a typhoid conjugate vaccine (TCV), ef...

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Detalhes bibliográficos

Principais autores:	Renzo Alfini, Roberta Di Benedetto, Martina Carducci, Vikram Paradkar, Hanuman Mallubhotla, Santosh Renukuntla, Dharmeshkumar Patel, Senthilkumar Manoharan, Mallikarjuna Panchakshari, Mahesh Kyasani, Nupur Sengupta, Laura B. Martin, Omar Rossi, Simona Rondini, Carlo Giannelli, Francesca Micoli
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-05-01
Colecção:	Frontiers in Immunology
Assuntos:	3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) linkage conjugation chemistry glycoconjugate Salmonella Paratyphi A Salmonella Typhi vaccine
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1726455/full
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