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Preclinical evaluation of a bivalent conjugate vaccine against Salmonella Typhi and Paratyphi A

IntroductionSalmonella enterica serovars Typhi and Paratyphi A cause millions of cases and thousands of deaths annually, predominantly affecting children in South and Southeast Asia. Following the licensure and World Health Organization (WHO) prequalification of a typhoid conjugate vaccine (TCV), ef...

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Kaydedildi:
Asıl Yazarlar: Renzo Alfini, Roberta Di Benedetto, Martina Carducci, Vikram Paradkar, Hanuman Mallubhotla, Santosh Renukuntla, Dharmeshkumar Patel, Senthilkumar Manoharan, Mallikarjuna Panchakshari, Mahesh Kyasani, Nupur Sengupta, Laura B. Martin, Omar Rossi, Simona Rondini, Carlo Giannelli, Francesca Micoli
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2026-05-01
Seri Bilgileri:Frontiers in Immunology
Konular:
3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) linkage
conjugation chemistry
glycoconjugate
Salmonella Paratyphi A
Salmonella Typhi
vaccine
Online Erişim:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1726455/full
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