Circulating peripheral helper T cells are expanded and associate with disease activity in granulomatosis with polyangiitis

Abstract Objectives Peripheral helper T (Tph) cells, a recently identified Th cell subset, have been implicated in various autoimmune diseases. However, their role in granulomatosis with polyangiitis (GPA) remains unclear. This study aimed to investigate the potential clinical significance of circul...

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Detalhes bibliográficos

Principais autores:	Hang Liao, Nanthicha Inrueangsri, Matthew A. Jackson-Wood, Samuel J. Bullers, Oliver Wood, Malte Borggrewe, Abraham Rutgers, Peter Heeringa, Wayel Habib Abdulahad
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-12-01
coleção:	Arthritis Research & Therapy
Assuntos:	Peripheral helper t cells Granulomatosis with polyangiitis Single-cell multi-omics Disease activity
Acesso em linha:	https://doi.org/10.1186/s13075-025-03701-w
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