Circulating peripheral helper T cells are expanded and associate with disease activity in granulomatosis with polyangiitis

Abstract Objectives Peripheral helper T (Tph) cells, a recently identified Th cell subset, have been implicated in various autoimmune diseases. However, their role in granulomatosis with polyangiitis (GPA) remains unclear. This study aimed to investigate the potential clinical significance of circul...

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Główni autorzy:	Hang Liao, Nanthicha Inrueangsri, Matthew A. Jackson-Wood, Samuel J. Bullers, Oliver Wood, Malte Borggrewe, Abraham Rutgers, Peter Heeringa, Wayel Habib Abdulahad
Format:	Artigo
Język:	Inglês
Wydane:	BMC 2025-12-01
Seria:	Arthritis Research & Therapy
Hasła przedmiotowe:	Peripheral helper t cells Granulomatosis with polyangiitis Single-cell multi-omics Disease activity
Dostęp online:	https://doi.org/10.1186/s13075-025-03701-w
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