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Distinct Neurotoxicity Profile of Listeriolysin O from Listeria monocytogenes

Cholesterol-dependent cytolysins (CDCs) are protein toxins that originate from Gram-positive bacteria and contribute substantially to their pathogenicity. CDCs bind membrane cholesterol and build prepores and lytic pores. Some effects of the toxins are observed in non-lytic concentrations. Two patho...

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Principais autores: Jana Maurer, Sabrina Hupp, Carolin Bischoff, Christina Foertsch, Timothy J. Mitchell, Trinad Chakraborty, Asparouh I. Iliev
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2017-01-01
Serier:Toxins
Fag:
listeriolysin O
meningitis
acute slices
varicosities
dendritic spines
Online adgang:http://www.mdpi.com/2072-6651/9/1/34
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