Targeting polyIC to EGFR over-expressing cells using a dsRNA binding protein domain tethered to EGF.
Selective delivery of drugs to tumor cells can increase potency and reduce toxicity. In this study, we describe a novel recombinant chimeric protein, dsRBEC, which can bind polyIC and deliver it selectively into EGFR over-expressing tumor cells. dsRBEC, comprises the dsRNA binding domain (dsRBD) of...
Na minha lista:
| Principais autores: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2016-01-01
|
| Colecção: | PLoS ONE |
| Acesso em linha: | http://europepmc.org/articles/PMC5012564?pdf=render |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|