Carbamate-based cannabinoids uncover a conserved lipid-sensing pocket in nociceptive TRPA1 and TRPV1 channels
TRPA1 and TRPV1 are nociceptive ion channels that integrate noxious chemical stimuli and are attractive targets for non-opioid analgesics. The phytocannabinoids cannabidiol (CBD) and cannabigerol (CBG) modulate both channels, but their pharmacological profiles and underlying structural determinants...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , |
|---|---|
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Elsevier
2026-08-01
|
| Σειρά: | Pharmacological Research |
| Θέματα: | |
| Διαθέσιμο Online: | http://www.sciencedirect.com/science/article/pii/S1043661826002343 |
| Ετικέτες: |
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!
|