Olivetol induces a non-genotoxic nucleolar DNA damage response via membrane-dependent stress signaling

Olivetol (5-pentylresorcinol) is a naturally occurring alkylresorcinol whose cellular mechanism remains poorly understood. Here, we show that olivetol induces a non-genotoxic nucleolar DNA damage response (n-DDR) in human cells. Although moderately cytotoxic, olivetol did not cause detectable genomi...

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Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Dmitry A. Deriglazov, Nadezhda V. Petrova, Artem V. Luzhin, Nataliya G. Pavlenko, Victor V. Tatarskiy, Eugene P. Kazakov, Igor I. Kireev, Alexander V. Kurkin, Anton M. Novoselov, Yuri M. Efremov, Peter S. Timashev, Sergey V. Razin, Artem K. Velichko
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Taylor & Francis Group 2026-12-01
Σειρά:	Nucleus
Θέματα:	Olivetol nucleolar DNA damage response ribosomal DNA R-loops TOPBP1 Treacle
Διαθέσιμο Online:	https://www.tandfonline.com/doi/10.1080/19491034.2026.2672818
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