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Inhibitory activity against carbonic anhydrase IX and XII as a candidate selection criterion in the development of new anticancer agents

Analysis of the literature data reveals that while inhibition of cancer-related carbonic anhydrase IX and XII isoforms continues to be an important enrichment factor for designing anticancer agent development libraries, exclusive reliance on the in vitro inhibition of these two recombinant isozymes...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Mikhail Krasavin, Stanislav Kalinin, Tatiana Sharonova, Claudiu T. Supuran
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis Group 2020-01-01
Schriftenreihe:Journal of Enzyme Inhibition and Medicinal Chemistry
Schlagworte:
Online-Zugang:http://dx.doi.org/10.1080/14756366.2020.1801674
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