EGFR-targeting polydopamine nanoparticles co-loaded with 5-fluorouracil, irinotecan, and leucovorin to potentially enhance metastatic colorectal cancer therapy

Abstract Despite all prevention programs, many cases of colorectal cancer (CRC) are diagnosed when they have already metastasized. Herein, chemotherapy is required, and combination of 5-fluorouracil, irinotecan, and leucovorin (FOLFIRI) is one of the first-line treatments chosen. However, it is so t...

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Detalhes bibliográficos

Principais autores:	Rania Djermane, Celia Nieto, Milena A. Vega, Eva M. Martín del Valle
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2024-11-01
coleção:	Scientific Reports
Assuntos:	Polydopamine nanoparticles Colorectal cancer 5-Fluorouracil Irinotecan Leucovorin Epidermal growth factor receptor
Acesso em linha:	https://doi.org/10.1038/s41598-024-80879-0
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