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Reducing muscleblind protein levels causes decreased DMPK transcripts and a muscle-specific chloride channel in myotonic dystrophy type one cell line

From a molecular perspective, myotonic dystrophy (DM) is characterised by the presence of abnormally long units of CUG and CCUG repeats that interact with some specific nuclear proteins to form foci in patient’s cells. It leads to entrapment of repeats in the nuclei to form foci in DM cells due to...

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Principais autores: Inyang Udosen, Monday Isaiah Akpanabiatu, Imo Yellow Sandy
Format: Artigo
Jezik:Inglês
Izdano: University of Sarajevo, Institute for Genetic Engineering and Biotechnology 2026-02-01
Serija:Genetics & Applications
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Online dostop:https://genapp.ba/editions/index.php/journal/article/view/262
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