Polydatin ameliorates early brain injury after subarachnoid hemorrhage through up-regulating SIRT1 to suppress endoplasmic reticulum stress

ObjectiveThis study aims to investigate the inhibitory effect of Polydatin (PD) on endoplasmic reticulum (ER) stress following subarachnoid hemorrhage (SAH) and to elucidate the underlying mechanisms.MethodsA standard intravascular puncture model was established to mimic SAH in mice. Neurological fu...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Yuwei Han, Guangzhi Hao, Song Han, Tingzhun Zhu, Yushu Dong, Ligang Chen, Xinyu Yang, Xiaoming Li, Hai Jin, Guobiao Liang
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Frontiers Media S.A. 2024-09-01
Sarja:	Frontiers in Pharmacology
Aiheet:	Polydatin subarachnoid hemorrhage endoplasmic reticulum stress SIRT1 early brain injury
Linkit:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1450238/full
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