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Kupffer cells abrogate homing and repopulation of allogeneic hepatic progenitors in injured liver site

Abstract Background Allogeneic hepatocyte transplantation is an emerging approach to treat acute liver defects. However, durable engraftment of the transplanted cells remains a daunting task, as they are actively cleared by the recipient’s immune system. Therefore, a detailed understanding of the in...

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Autors principals: Nasir Abbas, Kai You, Anteneh Getachew, Feima Wu, Muzammal Hussain, Xinping Huang, Yan Chen, Tingcai Pan, Yinxiong Li
Format: Artigo
Idioma:Inglês
Publicat: BMC 2024-02-01
Col·lecció:Stem Cell Research & Therapy
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Accés en línia:https://doi.org/10.1186/s13287-024-03656-w
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