Defective insulin secretory response to intravenous glucose in C57Bl/6J compared to C57Bl/6N mice
Objective: The C57Bl/6J (Bl/6J) mouse is the most widely used strain in metabolic research. This strain carries a mutation in nicotinamide nucleotide transhydrogenase (Nnt), a mitochondrial enzyme involved in NADPH production, which has been suggested to lead to glucose intolerance and beta-cell dys...
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| Автори: | , , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Elsevier
2014-12-01
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| Серія: | Molecular Metabolism |
| Предмети: | |
| Онлайн доступ: | http://www.sciencedirect.com/science/article/pii/S221287781400163X |
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