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Emerging role of long non-coding RNA SOX2OT in SOX2 regulation in breast cancer.

The transcription factor SOX2 is essential for maintaining pluripotency in a variety of stem cells. It has important functions during embryonic development, is involved in cancer stem cell maintenance, and is often deregulated in cancer. The mechanism of SOX2 regulation has yet to be clarified, but...

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Auteurs principaux: Marjan E Askarian-Amiri, Vahid Seyfoddin, Chanel E Smart, Jingli Wang, Ji Eun Kim, Herah Hansji, Bruce C Baguley, Graeme J Finlay, Euphemia Y Leung
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2014-01-01
Collection:PLoS ONE
Accès en ligne:http://europepmc.org/articles/PMC4090206?pdf=render
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